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ID Journal Club: New Approaches to MRSA Skin Infection in the ED

Program Description:

While it is intuitive that the use of the most appropriate antibiotic therapy may optimize treatment of MRSA-associated infections, selection of the most appropriate regimen is not.

Professionals treating patients at risk for MRSA infections must understand the spectrum of available agents and how to use their understanding of the corresponding drivers of efficacy, safety, and economics to implement evidence-based treatment approaches that best reduce the morbidity and mortality.

This activity consists of the review of a short video presentation and two primary references and answering a series of questions.  The references can be accessed on the journal club portal.

Target Audience:

This activity is intended to meet the needs of infectious disease specialists, critical care/pulmonologists, surgeons, pharmacists, nurses and other members of the health care practitioner team including infection control and microbiologists who have an interest in the management of Gram-positive infections.

Learning Objectives:

Upon completion of this knowledge activity, participants should be able to:

  • Discuss new data from research of basic microbiological sciences related to human disease with focus on the clinical implications of recent changes in methicillin-resistant Staphylococcus aureus (MRSA) as a pathogenic organism and the impact on patient outcomes.
  • Describe the updates to clinical diagnoses, preventative modalities, and therapeutics with a focus on new antimicrobial agents for the treatment of Gram-positive infections.
  • Review the possible impact of the Affordable Healthcare Act and acceleration of the development of Accountable Care Organizations while exploring best practices to select and prescribe the appropriate antibiotic(s) based upon the patient and infection type.

The overarching learning objectives of this activity are met with the review of this paper by understanding the clinical implication of the results of a prospective, randomized double-blind clinical trial of clindamycin versus TMP-SMX for the treatment of uncomplicated skin infections.


Acceditation Statement:

In support of improving patient care the Center for Education Development is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Credit Designation:

Center for Education Development designates this live educational activity for a maximum of 1.0 AMA PRA Category 1 Credit™, 1.0 CPE credit (UAN # 0498-0000-16-001-H01-P) or 1.0 ANCC credit.

Participants should claim credit commensurate with the extent of their participation in the activity. Participants must participate in the session and complete an activity evaluation before January 27, 2018. Pharmacists are required to pass the post-test with a minimum score of 70%.


Center for Education Development supports recommendations that will promote life long learning through continuing education. The following desirable physician attributes are addressed through this activity:

  • Provide patient-centered care
  • Employ evidence-based practice
  • Apply quality improvement

Required Hardware/Software:

The computer you plan to use should meet the following requirements:

  • Peripherals: Computer speakers or headphones
  • Monitor Screen Resolution: 320 x 480 or higher
  • Media Viewing Requirements: Adobe Reader, Microsoft PowerPoint, Flash Player & HTML

Faculty Bio:

Andrew Shorr, MD, MPH
Associate Chief, Pulmonary and Critical Care
Washington Hospital Center
Associate Professor of Medicine
George Washington University
Washington, DC


Andrew F. Shorr, MD, MPH, is Director (Interim) of Pulmonary and Critical Care at the Washington Hospital Center and Associate Professor of Medicine at Georgetown University. He received his undergraduate degree (public policy) from Princeton University, an MPH from Johns Hopkins University, and his medical degree from the University of Virginia. Dr Shorr’s research interests address healthcare outcomes, epidemiology in pulmonology/critical care, and infection in the hospitalized patient. He is an authority on healthcare outcomes research, a relatively new field requiring expertise in applying aspects of both traditional and social sciences. Health outcomes research can facilitate improvement in the practice and delivery of healthcare, thus limiting mortality and/or improving quality of health outcomes for patients.


Dr Shorr is the author/co-author of nearly 300 peer-reviewed manuscripts and book chapters. He has served on the editorial board of Chest, currently serves on the editorial board of Critical Care Medicine, and is a reviewer on several medical and critical care journals. He also served as a Fullbright Specialist Scholar in 2010.



Faculty reported the following financial relationships. A copy of CED's policy on resolving conflicts of interest can be found at 


Andrew F. Shorr, MD, MPH
Associate Chief, Pulmonary and Critical Care
Washington Hospital Center
Associate Professor of Medicine
Georgetown University Hospital
Washington, DC

Speaker for, consultant to or gotten research support from: Actavis, Astellas, AZ, Bayer, Cubist, Pfizer, Roche, Theravance, Trius, Carefusion. Merck, Wockhardt


Center for Education Development

Thomas Zimmerman, PhD (Reviewer, CED) has nothing to disclose.

Philip Scibilia, PhD (Reviewer, CED) has nothing to disclose

Danielle Amodio (Planner, CED) has nothing to disclose.

Support Statement:

This activity was supported by an unrestricted educational grant from Cubist
This activity is sponsored by Center for Education Development

Unlabeled and Investigational Usage:

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.


Created and published by Center for Education Development. Copyright © 2016 Center for Education Development. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of continuing medical education activities does not necessarily reflect the views and opinions of CED. Neither CED nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

References and Resources
Online Reference Downloadable Reference File Additional Resources


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